🔔#你的肝包太多油了嗎❗❗
🎯#脂肪肝 是國人常見的肝臟疾病,早期沒有明顯症狀,長期下來卻可能演變為肝炎、肝硬化或肝癌,迄今仍缺乏有效治療藥物💊。本院生物化學研究所 #陳瑞華 特聘研究員團隊發現一種操控細胞自噬(autophagy)的新機制,✅經動物實驗證明能 #抑制脂肪肝形成。
#什麼是細胞自噬
細胞自噬是細胞的主要資源回收機制,可消除細胞內的老舊廢物,或選擇性地清除細胞內的過多脂肪。
👨🔬👩🔬研究團隊發現一個名為UBE3C的泛素接合酶與一個名為TRABID的去泛素酶,共同調控細胞自噬因子VPS34,以達到細胞內的恆定狀態 👇
1⃣UBE3C藉分枝型泛素化修飾VPS34蛋白質,導致VPS34降解(degradation),被分解為小片段,#抑制 細胞自噬功能。
2⃣TRABID去除VPS34的泛素化修飾,使其不被降解,#促進 細胞自噬。
團隊以高脂飼料餵食小鼠誘發產生脂肪肝後,發現小鼠肝細胞內 #TRABID表現量下降,#無法啟動肝臟細胞的自噬作用。當這些小鼠被注射以腺病毒載體攜帶的TRABID基因,四週後從細胞切片觀察,✅肝臟油脂含量明顯減少,✅能抑制脂肪肝形成。
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陳瑞華表示,「🎉本研究對於脂肪肝的治療提供新契機,若能研發出提高TRABID表現或其活性的 #藥物,則可能阻斷脂肪肝的形成,進而預防肝功能異常、肝臟發炎等相關疾病。」
🌏研究成果於本(110)年2月發表在國際期刊《自然通訊》(Nature Communications)。
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Fatty liver is a prevalent liver disease in Taiwan and worldwide and is associated with obesity, diabetes and cardiovascular diseases. Although fatty liver is normally asymptomatic, its progression can lead to hepatitis, cirrhosis, and even liver cancer. The research team of Dr. Ruey-Hwa Chen at Institute of Biological Chemistry identifies a novel autophagy regulatory mechanism and a potential of preventing fatty liver progression by manipulating this mechanism. The study has recently been published on February 26 in Nature Communications.
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📌論文全文:https://www.nature.com/articles/s41467-021-21715-1
📌新聞稿:https://www.sinica.edu.tw/ch/news/6826
📌Press Release: https://www.sinica.edu.tw/en/news/6826
#生物化學研究所 #中研院研究 #細胞自噬 #Fattyliver
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✨想多跟我們互動?追蹤官方IG✨
https://www.instagram.com/academiasinica_official/?hl=zh-tw
✨中研大小事,訂閱《中研院訊》✨
我要訂閱👉https://newsletter.sinica.edu.tw/
同時也有1部Youtube影片,追蹤數超過8,540的網紅長谷川ろみの腸活研究所,也在其Youtube影片中提到,▼目次 00:00 はじめに 01:28 ぽっこりお腹の原因 03:09 ぽっこりお腹を解消する食べ物と科学的論文 06:37 ぽっこりお腹解消おすすめ食材 #ダイエット #体脂肪を減らす #ぽっこりお腹 ----------- ▽長谷川ろみの活動概要 ・元おデブ-20kg...
fatty liver disease 在 CheckCheckCin Facebook 八卦
【都市症狀】點解女士們成日頭暈暈?
#手袋裡總有婆仔藥油旁身
#改善體質才是治本之道
#星期二提升正能量
頭暈不一定是耳水不平衡
不少人都試過頭暈、眼花、耳鳴耳塞、噁心、冒汗、嘔吐等症狀,閉目休息一會狀況就會紓緩,西醫視之為耳水不平衡,中醫角度則屬於「眩暈」範圍,「眩」是指眼花,「暈」指頭暈,輕則如感到暈車浪,重則天旋地轉且難以站立。
眩暈成因眾多,最常見的原因為氣血不足、腎精不足、痰濕內阻及肝陽上亢。女性天生氣血較弱,有因為生理週期者,或者經歷懷孕、手術以致氣血虧虛,都會使氣血不足,腦失所養而出現眩暈。先天不足、年老體衰、思慮勞碌、房勞過度、熬夜等均會導致腎精不足,腎主骨,骨生髓,髓海不足就容易出現頭暈、耳鳴等症狀。另外所謂「無痰不作眩」,體內痰濕較重,痰濕阻塞經絡,引致氣血運行不暢,亦會引起暈眩。怒傷肝,急躁易怒個性亦會導致肝陽亢盛血上衝,出現頭暈症狀。
想從根本解決眩暈問題,必須了解自己體質對症下藥,留意以下各種眩暈成因及生活小貼士,眩暈發作時可以飲用天麻茯苓茶紓緩症狀。
氣血不足 — 適量進食補氣健脾養血食物,例如人參、紅棗、小米、薯仔、紅豆、靈芝等,做適量輕量運動如慢跑。
腎精不足 — 適量補充水份,避免熬夜及縱慾過度,多進食黑色養腎食物如黑木耳、黑豆、黑芝麻等。
痰濁中阻 — 戒吃生冷肥膩甜食,不宜進補,多進食健脾胃食物如淮山、薏米、白扁豆等。
肝陽上亢 — 調整心情,避免動怒,適度減壓,多喝有疏肝解鬱功效的花茶。
天麻茯苓茶
功效:健脾益胃,紓緩頭暈、頭脹、噯氣等症狀。
材料:天麻9克、茯苓15克、陳皮1角
做法:所有材料洗淨,鍋中加入約1000毫升水,放入全部材料,武火煮至水滾,調文火煮約1小時即可。
Causes of dizziness
Many people have experienced dizziness, blurred vision, clogged ear, tinnitus, nausea, sweating, vomiting and other symptoms. When you close your eyes, your condition may improve. Western medicine regards this as Meniere’s disease. It is simply “blurred vision and dizziness” in Chinese medicine. It can cause motion sickness, and feeling as though everything around you is spinning which makes it hard to stand still in serious cases.
There are many causes to dizziness. The most common causes are lack of blood and qi, insufficient kidney essence, internal resistance of phlegm and dampness and hyperactivity of the liver yang. Women’s qi and blood are weaker in nature. The menstrual cycle, or pregnancy or surgery may lead to qi and blood deficiency. It will reduce the qi and blood and the brain do not have enough nutrient supply which leads to dizziness. Innate deficiencies, age and weak body, excessive thinking, too much sexual activity, staying up late, will lead to insufficient kidney essence. The kidney is closely related to bone and marrow. When there is a lack of nutrients in the brain, you may be prone to dizziness, tinnitus and other symptoms. In addition, too much phlegm and dampness in the body will obstruct the meridians, causing poor qi and blood circulation which can also lead to dizziness. Anger hurts the liver, irritability will also lead to hyperactivity in the liver yang and dizziness symptoms.
If you want to relieve Dizziness, you must understand your body condition. Pay attention to the following causes of dizziness and tips. You can drink Poria tea with gastrodia to relieve those symptoms.
Insufficient qi and blood- appropriately consume ingredients that can replenish qi, strengthen spleen and nourish blood, such as ginseng, Chinese red dates, millet, potato, red bean and lucid Ganoderma. Moderately do low-intensity exercise such as slow jog.
Insufficient kidney essence- drink appropriate amount of water, avoid staying up late and having too much sex. Eat more black coloured ingredients that can nourish kidney such as black snow fungus, black bean and black sesame.
Excessive phlegm- avoid cold/raw, fatty, sweet and tonic food. Eat more ingredients that can strengthen spleen and stomach such as Chinese yam, coix seed and hyacinth bean.
Hyperactivity of the liver yang- adjust your mood, avoid being angry and appropriately relax your mind. Drink more floral tea that can relieve depression.
Poria tea with gastrodia
Effects: strengthens spleen and stomach, relieves symptoms such as dizziness, headache tension and burping.
Ingredients: 9g gastrodia, 15g poria, 1 dried citrus peel
Method: rinse all ingredients thoroughly. Combine all ingredients with 1000ml of water and cook on high heat until boiling. Turn to low heat and simmer for 1 hour.
#男 #女 #我有壓力 #我疲憊 #我狀態OK #氣虛 #血虛 #痰濕 #氣滯 #頭暈
fatty liver disease 在 營養師 Annie Lee 李杏榆 Facebook 八卦
印度抗炎法
疫情持續,全球每天都有新增個案,唯幾國家 / 城市可以力保不失,當中包括印度,暫時確診個案只有三宗。真心抵讚!除咗飲恒河水 (#曲,笑),仲有咩原因令到佢哋有咁強免疫力呢?
1)印度菜
印度菜,包括出名嘅印度咖哩,常用的配料包括洋蔥,番茄,蒜頭,香菜,再加上各種香料如薑,薑黃,茴香,辣椒等,全部都是高抗氣化的食材配料。
其中薑黃 (turmeric) 含有薑黃素(curcumin), 多份文件顯示,薑黃素屬安全,而且具有高效抗炎的效果(1),亦有研究顯示薑黃素有助提升肝臟排毒功能,改善非酒精性脂肪肝疾病 (Non-alcoholic fatty liver disease, NAFLD) (2)。
而因印度教徒不吃牛,伊斯蘭教徒不吃豬,所以印度菜中多以植物類為主 (包括蔬菜,豆類,根莖類如薯仔,胡蘿蔔等)。至於肉類則以羊,雞,以及魚為主。
經常攝取紅肉會增加身體發炎風險,尤其是肥胖人士 (3)。
2)印度天氣炎熱猛太陽,除了太陽有殺菌的作用外,多曬太陽有助吸收維他命D,有助增強免疫力。
所以要提升免疫力,平時煮餸不妨多使用新鮮香料,減少加工調味料;減少進食紅肉,多進食白肉,海鮮類,以及豆類作為蛋白質補充。
另外,找機會多曬太陽,或進食維生素D,這些全部都有助提升免疫力。
#印度防疫 #全民抗炎
#抗氧化 #薑黃 #抗炎
#一個都不能少
#由上年六月講到宜家
#香港人加油
#營養師 #Nutritionist #AnnieLee
1. J Altern Complement Med. 2003 Feb;9(1):161-8.
2. Integrative Medicine Research, Volume 8, Issue 1, March 2019, Pages 57-61
3. Am J Clin Nutr. 2014 Feb;99(2):352-60. doi: 10.3945/ajcn.113.075663. Epub 2013 Nov 27.
fatty liver disease 在 長谷川ろみの腸活研究所 Youtube 的評價
▼目次
00:00 はじめに
01:28 ぽっこりお腹の原因
03:09 ぽっこりお腹を解消する食べ物と科学的論文
06:37 ぽっこりお腹解消おすすめ食材
#ダイエット
#体脂肪を減らす
#ぽっこりお腹
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▽長谷川ろみの活動概要
・元おデブ-20kg/アラフォー
・発酵ライフ推進協会 通信校 校長 &プロデュース
・東京商工会議所認定 健康経営アドバイザー
・腸活メディア「腸内革命」編集長 & 講師
・著書「発酵菌早わかりマニュアル」
・2019/6~腸活youtuber始めました!
Twitter:https://twitter.com/haseromi
Instagram:https://www.instagram.com/hasegawaromi/
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▼関連動画
男女別、ぽっこりお腹の原因と解消方法。【内臓脂肪の落とし方&便秘解消】
https://www.youtube.com/watch?v=kCiSuAJm75g
痩せない原因の反り腰を徹底解消!ぽっこりお腹&太もも痩せのためのトレーニング
https://www.youtube.com/watch?v=WOcmxkggd5U
あなたの下っ腹の脂肪が取れない理由
https://www.youtube.com/watch?v=51bGjLRPxoM
ポッコリお腹が痩せない原因の反り腰を10秒で解消できるストレッチ
https://www.youtube.com/watch?v=ZGv1pMmlI5s
▼参考論文&研究
海藻由来フコキサンチンの抗肥満作用
https://www.jstage.jst.go.jp/article/oleoscience/12/10/12_503/_pdf/-char/ja
The effects of Xanthigen? in the weight management of obese premenopausal women with non‐alcoholic fatty liver disease and normal liver fat
https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/j.1463-1326.2009.01132.x
Fucoxanthin From Edible Seaweed, Undaria Pinnatifida, Shows Antiobesity Effect Through UCP1 Expression in White Adipose Tissues
https://pubmed.ncbi.nlm.nih.gov/15896707/
※この動画は、診断・治療または医療アドバイスを提供しているわけではありません。あくまで情報提供のみを目的としています。
※診断や治療に関する医療については、医師または医療専門家に相談してください。この動画は医療専門家からのアドバイスに代わるものでもありません。
fatty liver disease 在 Non-alcoholic fatty liver disease - YouTube 的八卦
Nonalcoholic fatty liver disease is actually a spectrum of disease, going from least to most severe—steatosis, steatohepatitis, fibrosis, ... ... <看更多>