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#11. Vitamin D: the light side of sunshine - Nature

Under normal circumstances, most vitamin D is derived from the action of ultraviolet (UV) light on substrate 7-dehydrocholesterol in skin. Low ...

#12. Overview of vitamin D - UpToDate

Very few foods naturally contain vitamin D (fatty fish livers are the ... uptake mechanism for vitamin D-binding protein/25-(OH)D3 complex.

#13. Vitamin D Metabolism and Function - ALPCO

Calcitriol is produced in the cells of the proximal tubule of the nephron in the kidneys by the action of 25-hydroxyvitamin D3 1-alpha-hydroxylase, a ...

#14. MECHANISMS IN ENDOCRINOLOGY: Vitamin D and fertility

In men, vitamin D is positively associated with semen quality and androgen status. Moreover, vitamin D treatment might increase testosterone levels.

#15. Molecular Mechanisms of Vitamin D Action | SpringerLink

By recruiting complexes of either coactivators or corepressors, ligand-activated VDR-RXR modulates the transcription of genes encoding proteins ...

#16. Vitamin D and Cancer | Endocrinology - Frontiers

Vitamin D acts like a transcription factor that influences central mechanisms of tumorigenesis: growth, cell differentiation, and apoptosis.

#17. (PDF) Vitamin D: Production, Metabolism, Action, and Clinical ...

PDF | Vitamin D3 and its plant‐derived counterpart vitamin D2 (collectively ... The mechanism of action of the active form of vitamin D, 1,25‐(OH)2D, ...

#18. The Biological Activities of Vitamin D and Its Receptor in ...

2. Some Genomic Functions of the Vitamin D Receptor (VDR) ... ]. These may be the biological mechanisms by which vitamin D enhances cellular responsiveness to ...

#19. Vitamin D and depression: mechanisms, determination and ...

Key Words: depression, vitamin D, pathological mechanisms, neuroactivities, determination. Depression is a public health concern with no current.

#20. The importance of vitamin D - OAText

Vitamin D can induce bone resorption through the molecular mechanism of the receptor activator for nuclear factor κB ligand (RANKL) [30], osteoblasts have ...

#21. Chapter 28. Vitamin D: Production, Metabolism, Mechanism of ...

VITAMIN D : PRODUCTION,. METABOLISM,. AND MECHANISM. OF ACTION I 141. Shoback D 1999 Expression and signal transduction of calcium-.

#22. Metabolism and Mechanism of Action of Vitamin D - Annual ...

Vitamin D, like the three other fat-soluble vitamins, has defied definition of its mechanism of action for over SO years. However, during the past several ...

#23. Mechanisms for vitamin D resistance in renal failure

1,25-dihydroxyvitamin D [1,25(OH)2D3], the hormonal form of vitamin D, controls serum levels of parathyroid hormone (PTH) and parathyroid hyperplasia. Both 1,25 ...

#24. Dietary Reference Intakes for Calcium and Vitamin D - The ...

In the second mechanism, calcitriol plays an essential role in the mobilization of calcium from bone, a process requiring PTH (Garabedian et al., 1972; Lips, ...

#25. Vitamin D | Osmosis

We'll focus on Vitamin D, which along with parathyroid hormone, helps increase calcium levels, whereas calcitonin helps lower them. The majority of the ...

#26. Vitamin D and Its Synthetic Analogs - ACS Publications

His work focuses on mechanisms of gene regulation by nuclear hormones, in particular on vitamin D. At present Prof. Carlberg has projects on ...

#27. The importance of vitamin d metabolism as a potential ...

Recent clinical trials also reported that vitamin D ... Vitamin D: Overview of molecular mechanism and multifaceted functions beyond ...

#28. Vitamin D | You and Your Hormones from the Society

Vitamin D is a hormone produced by the kidneys that helps to control the ... and stroke, although the direct relevance and mechanisms underlying these ...

#29. Vitamin D and Depression: Cellular and Regulatory ...

The increase in ROS that occurs during inflammation may induce depression through a number of mechanisms such as an alteration in the formation ...

#30. Vitamin D3 (cholecalciferol)

What is its mechanism of action?^. After its conversion from Vitamin D3, calcitriol exerts its effects on the body by ...

#31. Drisdol, Calciferol (vitamin D) dosing, indications, interactions ...

vitamin D (Rx, OTC) ; Mechanism of Action. Stimulates calcium and phosphate absorption from small intestine; stimulates phosphate resorption at renal tubule; ...

#32. Steroid Hormone Vitamin D | Circulation Research - AHA ...

As one of the 4 fat-soluble vitamins (A, D, E, and K), its lipophilicity requires special mechanisms to pass through the aqueous environment ...

#33. Mechanisms underlying the effect of vitamin D on the immune ...

In particular, vitamin D and VDR deficiency exacerbates experimental autoimmune diseases such as inflammatory bowel disease (IBD). IBD develops due to an immune ...

#34. Vitamin D Synthesis | Biology for Majors II - Lumen Learning

In the presence of sunlight, a form of vitamin D3 called cholecalciferol is synthesized from a derivative of the steroid cholesterol in the skin. The liver ...

#35. Mechanisms Involved in the Relationship between Vitamin D ...

In a randomized, double-blind clinical trial in obese Caucasian adolescents (BMI > 95th), the effect of vitamin D3 supplementation on insulin action and β-cell ...

#36. Vitamin D, Immune System & SARS-CoV-2 (COVID-19)

#37. What Role Does the Sun Play in Vitamin D Synthesis?

When the sun's ultraviolet rays touch the skin, they convert the precursor to a molecule called vitamin D3, which then follows a metabolic ...

#38. The Mechanism for Phenytoin (Dilantin) Associated ...

Vitamin D can come from one of three sources: sunlight exposure to uncovered skin, overt-the-counter (OTC) vitamin D supplements, and through foods. Regardless ...

#39. Mechanism of vitamin D action and its regulation - American ...

Most of the biological actions of 1,25(OH)2D3, the hormonal form of vitamin D, are mediated by the vitamin D receptor (VDR), a member of the steroid/thyroid ...

#40. Evidences for a protective role of vitamin D in COVID-19

Major clinical reports show that vitamin D deficiency contribute to acute ... Proposed mechanism whereby 1,25(OH) D -VDR (D-hormone) signalling acts on the ...

#41. Potential Molecular Mechanisms of the Anti-cancer Activity of ...

Vitamin D, or more precisely its active metabolite calcitriol (1,25-(OH)2D3), plays a fundamental role in bone metabolism and differentiation as well as in ...

#42. Vitamin D Deficiency Symptoms & Supplement Side Effects

What is vitamin D-oral, and how does it work (mechanism of action)?; What are ...

#43. Calcitriol-modulated human antibiotics - Elsevier

The literature on their secretion mechanisms, levels in different organic fluids, mechanism of action, and relationship with vitamin D is reviewed here.

#44. Everything you always wanted to know about vitamin D but ...

Mechanism of acnon. – Vitamin D Receptor. – Gene transcripnon: inducnon/repression. • Biological Acnon. – Classical effects: Calcium / phosphate homeostasis.

#45. Vitamin D. Physiology. Its use in the treatment of osteoporosis

Vitamin D is actually not a vitamin in the strict sense of the word. ... These are molecules with different pharmacological mechanisms that ...

#46. Human Plasma Transport of Vitamin D after Its ...

Transport of vitamin D3 from its sites of cutaneous synthesis ... calciferol to be the physiological mechanism of precursor supply (2-5).

#47. Vitamin D - wikidoc

Once vitamin D is produced in the skin or consumed in food, it is converted in the liver and kidney to form 1,25 dihydroxyvitamin ...

#48. Vitamin D Biochemistry - News Medical

Cholecalciferol, which is the side chain of vitamin D3, is then carried to the liver, where a mitochondrial hydroxylase enzyme introduces a ...

#49. Mechanisms of absorption of vitamin D3 delivered in protein ...

... regarding the bioavailability and absorption mechanism of the bioactive without fat. To provide answers, we chose vitamin D3 (VD3) as a model lipophi.

#50. VITAMIN D: METABOLISM, MOLECULAR MECHANISM OF ...

—1,25-Dihydrox- vitamin D3 [1,25(OH)2D3] is the hormonally active form of vitamin D. The genomic mechanism of 1,25(OH)2D3 action involves the ...

#51. Vitamin D metabolism and molecular modes of action - Via ...

receptor (VDR) has been generated [1]. This knowledge has provided new insights into plausible mechanisms by which vitamin D could exert activities across a ...

#52. The vitamin D receptor: contemporary genomic approaches ...

Nevertheless, a re-assessment of many of the earlier findings of the mechanisms associated with VDR gene regulation is now underway due to ...

#53. Skin as the Site of Vitamin D Synthesis and Target Tissue for 1 ...

The skin is responsible for producing vitamin D. During exposure to sunlight, ... et al: Functions and mechanism of action of the 1,25-dihydroxyvitamin D, ...

#54. Vitamin D: Beyond Metabolism - SAGE Journals

Interest in vitamin D and the VDR gene is increasing as putative ... Such vitamin D–independent mechanisms of regulating iCa2 + are thus well ...

#55. VITAMIN D-METABOLISM - SlideShare

Vitamin D Gandham. ... are absorbed from upper small intestine and bile is essential Mechanism: vitamin D3 and D2 form mixed micelles by ...

#56. Vitamin D - eClinpath

Vitamin D is mostly thought of with respect to calcium and phosphate status, ... has been postulated to be the mechanism behind hypercalcemia in dogs with ...

#57. Effects and Mechanisms of Action of Vitamin D in Multiple ...

Vitamin D supplementation is related to immunological benefits, acting in the regulation of the immune system, inflammation, recovery of cells ...

#58. Fasting-Induced Transcription Factors Repress Vitamin D ...

Low 25-hydroxyvitamin D levels correlate with the prevalence of diabetes; however, the mechanisms remain uncertain.

#59. Potential immunomodulatory effects of vitamin D in the ...

~3.0) (13,14). The mechanism of infection of SARS-CoV-2 involves the spike protein of SARS-CoV-2 binding to the angiotensin-converting enzyme 2 ...

#60. Vitamin D

Synthesis mechanism (form 3) · 1. Vitamin D3 is synthesized from 7-dehydrocholesterol, a derivative of cholesterol, which is then photolyzed by ultraviolet light ...

#61. Altered Vitamin D Metabolism in Health and Disease

The aim of this dissertation was to explore mechanisms of altered vitamin D homeostasis in patients with cystic fibrosis (CF) and in pregnant women, ...

#62. Vitamin D and Metabolites - Warde Medical Laboratory

The active form of vitamin D is 1, 25 (OH) 2 vitamin D. (3) It is a hormone that responds to decreased serum calcium levels by stimulating the absorption of ...

#63. An Update on Vitamin D Metabolism - Semantic Scholar

However, other mechanisms are likely to exist, since suppression of CYP2R1 by starving was observed also in PGC1α knockout mice. Aatsinki et al.

#64. Vitamin D and COVID-19: evidence and recommendations for ...

The mechanism for the relationship between obesity and vitamin D deficiency is incompletely understood. It may partly reflect sequestration ...

#65. Chemical Conversion of Vitamin D 3 to Calcitriol Lactone - De ...

The Need for New Vitamin D Analogues: Mechanisms of Action and Clinical Applications · Future Prospects for Vitamin D Analogs.

#66. Vitamin D: Marker or Mechanism of Action? - Cancer ...

Evidence for the mechanism of action of vitamin D in carcinogenesis from laboratory studies is mainly derived from experiments using the ...

#67. UNRAVELING THE ENIGMA OF VITAMIN D - National ...

D. Increasingly, researchers are learning that vitamin ... vitamin D is a hormone, chemically akin to familiar ... the mechanism of calcium control.

#68. The Important Role of Vitamin D - Pharmacy Times

Vitamin D, which aids the body's immune and skeletal systems in various ways, is available in many foods and in many OTC nutritional ...

#69. vitamin D, blood pressure, hypertension - Universitas Gadjah ...

Further Understanding about the Mechanism of Vitamin D on Blood Pressure. Farapti Farapti Department of Nutrition, Faculty of Public Health, ...

#70. Vitamin D - Uses, Side Effects, and More - WebMD

There are different forms of vitamin D, including ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3). Vitamin D is found in fish, eggs, ...

#71. Endocrine-related Organs and Hormones

Calcitriol acts on the intestine, kidneys, and bones to maintain normal levels of blood calcium and phosphorus. Vitamin D.

#72. VDR gene: MedlinePlus Genetics

The VDR gene provides instructions for making a protein called vitamin D ... Although the mechanism is not completely understood, the VDR protein is also ...

#73. Basic and Clinical Concepts Related to Vitamin D Metabolism ...

A complex and elegant biochemical mechanism is thought to function at the pivotal kidney site to modulate the biosynthesis of this most active ...

#74. Mechanisms of vitamin D action in skeletal muscle – June 2019

Vitamin D inadequacy or deficiency is associated with muscle fibre atrophy, increased risk of chronic musculoskeletal pain, sarcopenia and ...

#75. vitamin D | Biosynthesis, Benefits, & Recommended Daily Intake

Vitamin D, any of a group of fat-soluble vitamins that plays a role in calcium metabolism in animals. The primary source of vitamin D is sunlight exposure, ...

#76. VDR (VITAMIN D RECEPTOR) – Nurcamein

Vitamin D receptors (VDRs) probably mediate all vitamin D actions in higher vertebrates. VDRs are located predominantly in the nucleus of cells, ...

#77. Vitamin D Mechanism of Action | Time of Care

Vitamin D Mechanism of Action. ENDOCRINOLOGY. This photo is from Oregonstate.edu. print. Related. Causes of Hypophosphatemia December 2, ...

#78. The vitamin D deficiency pandemic and consequences for ...

Vitamin D, the sunshine vitamin, is important for childhood bone health. ... These mechanisms may be responsible for why vitamin D sufficiency decreases ...

#79. Vitamin D and neurocognitive function | CIA - Dove Medical ...

Keywords: vitamin D, 25(OH)D level, cognition, mild cognitive ... of 1,25(OH)2D in the blood is regulated via a feedback mechanism by 1 ...

#80. Vitamin D Deficiency Linked With Increased COVID-19 Severity

Vitamin D is most often recognized for its role in bone health, but low levels of the supplement have been associated with a range of autoimmune ...

#81. Pre-infection deficiency of vitamin D is associated with ...

In a new study, researchers show a correlation between vitamin D deficiency and COVID-19 severity and mortality. The study is among the ...

#82. ASK THE NUTRITIONIST: The importance of Vitamin D

Vitamin D3 is so essential for our health that we have a built-in mechanism to ensure we get enough, irrespective of dietary intake.

#83. Vitamin D Receptor (VDR or Calcitriol ... - Yahoo Finance

The report provides detailed coverage of the pipeline landscape for this mechanism of action, equipped with data from multiple sources with ...

#84. Vitamin D Deficiency and Dependency - Nutritional Disorders

Diagnosis involves measurement of serum 25(OH)D (D2 + D3). Treatment usually consists of oral vitamin D; calcium and phosphate are supplemented as needed.

#85. Vitamin D supplements may have a protective effect on the ...

From the paper: Autoimmune diseases are a group of heterogeneous conditions with similar underlying pathogenetic mechanisms and together are ...

#86. Chapter 8. Vitamin D

Vitamin D is required to maintain normal blood levels of calcium and ... both by a direct mechanism and by a spleen cell-mediated indirect mechanism. Proc.

#87. Vitamin D and the Lung: Mechanisms and Disease Associations

Mechanisms and Disease Associations Augusto A. Litonjua. and in fact, some studies suggest a detrimental effect of vitamin D supplementation on the ...

#88. Vitamin D: Volume 2: Health, Disease and Therapeutics

... 841–842 mechanism of action of 1, 25(OH)2D3 in colon cancer, 844–852 vitamin D effect on colon cancer-promoting pathways, 900 vitamin D hydroxylases and ...

#89. Vitamin D: Oxidative Stress, Immunity, and Aging

The mechanisms of 1,25(OH)2D3-mediated SLE disease inhibition in MRL/lpr mice ... D DePenDence of eRythemaL Damage PReVention One vitamin D mechanism that ...

#90. Sunlight, Vitamin D and Skin Cancer - 第 294 頁 - Google 圖書結果

Three potential mechanisms for such protection were examined. The first mechanism focuses on the role of vitamin D signaling in keratinocyte proliferation ...

#91. Vitamin D: Two-Volume Set - 第 712 頁 - Google 圖書結果

Several lines of evidence demonstrate that vitamin D regulation of renin is independent ... the basic regulatory mechanisms that control renin production, ...

#92. vitamin D mechanism - InlifeHealthCare

vitamin D mechanism. Published March 24, 2014 at 610 × 525 in Health Benefits Of Vitamin D And Its Significance · vitamin D mechanism.

#93. Vitamin D Receptor (VDR or Calcitriol ... - Herald Chronicle

The report provides detailed coverage of the pipeline landscape for this mechanism of action, equipped with data from multiple sources with complete pipeline ...

#94. Overdose Among the Opioid-Naive; Bed Nets and Malaria

Also in TTHealthWatch: Omega-3s, vitamin D, and autoimmune ... This is a low-cost, highly effective mechanism for preventing malaria.

#95. The metabolism and mechanism of action of 1,25 ... - CORE

It binds 25-hydroxyvitamin D3 with high affinity and binds other vitamin D metabolites, such as vitamin D3 and 1 ,25-dihydroxyvitamin D3, with lower affinity.